Learning Objectives

At the end of this educational activity, participants should be able to:

  • Explain the factors that constitute barriers to full functional recovery from depression including medication side effect management, cognitive impairment and optimal multimodal therapy strategies.
No CME credit will be offered for this activity.

Target Audience

Psychiatrists, Primary Care Physicians, Nurse Practitioners, and Physician Assistants


  • Director of Research, Depression Clinical and Research Program, Massachusetts General Hospital
    Associate Professor of Psychiatry, Harvard Medical School

CME Information



No CME credit will be offered for this activity. This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education. This activity has expired. CME/CE Released: 3/15/2010; Valid for credit through 3/15/2013. 

Credit Designation

Even though this event is no longer accredited, providing information regarding planning, disclosure, and conflict of interest is important to us.This activity was accredited by McLean Hospital. 



Policy on Faculty and Provider Disclosure
It is the policy of McLean Hospital that faculty and providers disclose real or apparent conflicts of interest relating to the topics of this educational activity, and also disclose discussions of unlabeled/unapproved uses of drugs or devices during their presentation(s). McLean Hospital has established policies in place that will identify and resolve all conflicts of interest prior to this educational activity.




The following planners of this activity have indicated that neither they nor their families have a significant financial interest or affiliation with the manufacturer of any commercial products or provider of commercial services:

Robert J. Birnbaum, MD, PhD: Planner

John A. Fromson, MD: Planner, reviewer

Anan Nathif, EdM: Planner

Tristan Gorrindo, MD: Planner

Hardware/Software Specifications: 

This internet-based CME activity is best experienced using Internet Explorer 8+, Mozilla Firefox 3+, Safari 4+. This Web site requires that JavaScript and session cookies be enabled. Certain activities may require additional software to view multimedia, presentation, or printable versions of the content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Flash, Adobe Acrobat, Microsoft PowerPoint, and Windows Media Player.

Optimal System Configuration:
Flash Player: Adobe Flash Player 10.1+
Browser: Firefox 3+, Internet Explorer 8.0+, Safari 4.0+, or Google Chrome 7.0+
Operating System: Windows XP+ or Mac OS X 10.4+
Internet Connection: 1 Mbps or higher

Minimum Requirements:
Windows PC:
500-MHz Pentium II; Windows XP or higher; 128 MB RAM; Video Card at least 64MB of video memory; Sound Card at least 16-bit; Macromedia Flash Player 10 or higher, audio playback with speakers for programs with video content; Firefox 1.1+, Internet Explorer 7.0+, Safari 1.0+, Google Chrome, or Opera
Mac OS X 10.3 or higher with latest updates installed; 1.83MHz Intel Core Duo or faster; RAM: 128MB or more; Video Card: at least 64MB of video memory; Sound Card: at least 16-bit



The following speakers and/or planners have reported receiving something of value from a company whose product may be germane to the content of their presentations:

David Mischoulon, MD, PhD

Research Support:

Laxdale (Amarin); Nordic Naturals; Ganeden


Bristol-Meyers Squibb Company



Royalty/patent, other income: 

Royalties from Back Bay Scientific for PMS Escape (patent application pending)

Reed Medical Education; MGH Psychiatry Academy