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Iosifescu, Dan, MD, MMSc

Director, Mood and Anxiety Disorders Program, Mount Sinai Medical Center
Associate Professor of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai


Dr. Dan Iosifescu is the Director of the Mood and Anxiety Disorders Program and Associate Professor of Psychiatry and Neuroscience at Mount Sinai Medical School.  Dr. Iosifescu’s research is focused on biological markers of treatment outcome in mood disorders, using neuroimaging (MRI, MRS) and neurophysiology (quantitative EEG) techniques to investigate structural, biochemical, and functional brain abnormalities in mood disorders and their impact on clinical treatment.  Dr. Iosifescu is also interested in the impact of co-morbid medical illness, especially vascular disease, on treatment outcome in mood disorders.  Dr. Iosifescu has continuously received independent funding from NIMH since 2003 (as well as from private foundations); he is currently funded by an NIMH R01 to study treatments for cognitive deficits in bipolar disorder.

After receiving his medical degree from the Institute of Medicine and Pharmacy in Bucharest, Romania, Dr. Iosifescu completed his internship and psychiatry residency at Massachusetts General Hospital and McLean Hospital, serving as chief resident in consultation-liaison psychiatry.  His research training included a neuroimaging fellowship in the Neuroscience Laboratory at Harvard Medical School, a psychopharmacology fellowship in the MGH Mood and Anxiety Disorders Institute, and a fellowship in the Clinical Investigator Training Program at Harvard and MIT.  In parallel Dr. Iosifescu received a Master of Medical Science degree from Harvard University. Until April 2010 Dr. Iosifescu was Associate Professor of Psychiatry at Harvard Medical School and Director of Translational Neuroscience in the Depression Clinical and Research Program and Site Director of the Bipolar Trials Network, both at Massachusetts General Hospital.

Dr. Iosifescu has authored more than 100 papers in peer-reviewed medical journals, 14 book chapters and more than 100 abstracts.   He received a series of prestigious prizes: the NARSAD Young Investigator Award (which he received twice), the Kaplen Award and the Livingston Award from Harvard Medical School, the APA Young Investigator Award, the NCDEU New Investigator Award, and a National Institute for Mental Health K23 Career Development Award.   Dr. Iosifescu was also designated amount the “Best Doctors in America” in all editions of “Best Doctors” since 2005.