Learning disorders are one of the most common neurodevelopmental disorders and have a significant impact on psychosocial functioning. Individuals with learning disorders are at greater risk for psychiatric disorders (e.g., depression, anxiety), as well as other neurodevelopmental disorders (e.g., attention deficit hyperactivity disorder), and neurological conditions (e.g., epilepsy). They are also at greater risk of diminished educational, occupational, and financial gains, as well as incarceration, especially for those impacted by racial and economic disparities. This course examines neuropsychological profiles associated with each disorder, common comorbidities, and their developmental progression, including what might be expected with appropriate intervention. We discuss diagnostic challenges and how eligibility for special education services and accommodations in school is determined.